" /> Invasive Adenocarcinoma of the Mouse Prostate Gland - CISMeF





Preferred Label : Invasive Adenocarcinoma of the Mouse Prostate Gland;

Alternative definition : MMHCC: Well differentiated in humans generally restricted to transition zone (clear cell) carcinomas, often associated with BPH nodules. As such anatomic associations have not been observed or do not occur in mice and carcinomas morphologically similar to human well differentiated prostate carcinomas have not been observed, well differentiated adenocarcinoma (conceptually and morphologically similar to human term) should not be used as a mouse designation at the current time.; MMHCC: Invasive carcinoma is the penetration of malignant epithelial cells (that demonstrates unequivocal glandular proliferation) through the basement membrane into the surrounding stroma (Degree of differentiation will be defined based on the extent of glandular proliferation).;

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08/07/2025


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