Preferred Label : Gallium Ga 68 GPC3-targeted Peptide RYZ811;
NCIt synonyms : Gallium Ga 68-labeled GPC3-targeted Peptide RYZ811; Ga-68 GPC3-targeted Peptide RYZ811; Ga 68 GPC3-targeted Peptide RYZ811;
NCIt definition : A radioconjugate composed of a glypican-3 (GPC3; GPC-3)-binding peptide conjugated
to the radionuclide gallium Ga 68, with potential use as a tracer for GPC3-expressing
tumor cells during positron emission tomography (PET). Upon administration of gallium
Ga 68 GPC3-targeted peptide RYZ811, the GPC3-binding moiety targets and binds to GPC3-expressing
tumor cells. Upon binding, GPC3-expressing tumor cells can be detected during PET.
GPC3, a heparan sulfate proteoglycan and a member of the glypican family, is overexpressed
on certain tumor cell types while minimally expressed in normal, healthy cells. GPC3
plays an important role in tumor cell proliferation in various tumor cell types.;
Molecule name : RYZ-811; RYZ 811;
Origin ID : C216945;
concept_is_in_subset
- has_target
