Preferred Label : EGFR Mutant-specific Inhibitor DZD6008;
NCIt synonyms : EGFR Inhibitor DZD6008;
NCIt definition : An orally available, blood-brain-barrier (BBB) penetrant, mutant-specific inhibitor
of the receptor tyrosine kinase epidermal growth factor receptor (EGFR), with potential
antineoplastic activity. Upon oral administration, EGFR inhibitor DZD6008 targets,
binds to and inhibits certain EGFR mutations. This prevents EGFR-mediated signaling
and may result in the inhibition of tumor growth in susceptible tumor cells. EGFR
plays a major role in tumor cell proliferation and is often mutated in cancer cells.;
Molecule name : DZD-6008; DZD 6008;
Origin ID : C216122;
concept_is_in_subset
- has_target
