Preferred Label : Fluorine F 18 Trioxolane;
NCIt synonyms : 18F-TRX; Fluorine F 18 TRX;
NCIt definition : A labile iron pool (LIP) radiotracer composed of 1,2,4-trioxolane (TRX) radiolabeled
with the positron-emitting isotope fluorine F 18, with potential cancer cell imaging
activity during positron emission tomography (PET). As tumor cells accumulate more
iron than normal, healthy cells due to their increased need for energy to proliferate,
when fluorine F 18 TRX is administered, it is selectively taken up by rapidly proliferating
tumor cells, reacts with ferrous iron (Fe2 ), and accumulates in tumor cells. Upon
PET, tumor cells.;
Origin ID : C215713;
concept_is_in_subset
