Phosphatidylinositide 3-Kinase Inhibitor

Preferred Label : Phosphatidylinositide 3-Kinase Inhibitor;

NCIt synonyms : PI3-Kinase Inhibitors; Phosphatidylinositol 3-kinase Inhibitor; Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Inhibitor;

NCIt related terms : PI3K Inhibitor;

NCIt definition : Any substance that inhibits phosphatidylinositol 3-kinase (phosphatidylinositide 3-kinase), an enzyme that catalyzes the phosphorylation of the 3 position hydroxyl group of the inositol ring of phosphatidylinositol and functions as an intracellular signal transducer in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. Inhibition of phosphatidylinositol 3-kinase produces antiproliferative and antiangiogenic effects.;

ChEBI ID : CHEBI:50914;

Details

Origin ID

C2152;

UMLS CUI

C1519050;

Manual BTNT mappings - CISMeF
- Phosphatidylinositol-3-kinase (Pi3K) inhibitors [ATC Code]
See also inter- (CISMeF)
- Substance with phosphoinositide 3 kinase inhibitor mechanism of action (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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