Preferred Label : Zirconium Zr 89-DFO-starPEG;
NCIt synonyms : Zr89-DFO-starPEG; (89Zr)DFO-starPEG; 89Zr-labeled DFO-starPEG; 89-Zr-DFO-star Polyethylene Glycol;
NCIt definition : A radioconjugate containing starPEG, a 4-armed polyethylene glycol (PEG)-based nanodrug
carrier moiety, linked, via the chelator desferrioxamine (DFO), to the radioisotope
zirconium Zr 89 (Zr89), with potential use as an imaging agent upon positron emission
tomography (PET) imaging. Upon administration, starPEG is taken up by tumors due to
enhanced permeability and retention (EPR) effect. Upon PET imaging, EPR-mediated tumor
uptake and distribution of the nanodrug carrier may be visualized.;
Origin ID : C215131;
concept_is_in_subset