Preferred Label : mRNA Neoantigen Cancer Vaccine XH001;
NCIt synonyms : Neoantigen mRNA Cancer Vaccine XH001; mRNA Personalized Cancer Vaccine XH001; mRNA-based Neoantigen Cancer Vaccine XH001;
NCIt definition : A therapeutic personalized cancer vaccine consisting of mRNA encoding a patient's
tumor-specific neoantigens, with potential immunomodulatory and antineoplastic activities.
Upon administration of the mRNA neoantigen cancer vaccine XH001, the mRNA is taken
up by and translated into the desired neoantigens in the patient's antigen-presenting
cells (APCs), primarily dendritic cells (DCs), and presented by major histocompatibility
complex (MHC) molecules on the surface of the APCs. This may activate tumor antigen-specific
T-cells to kill cancer cells expressing these neoantigens.;
Molecule name : XH 001; XH-001;
Origin ID : C215088;
concept_is_in_subset
