Ad5-encoding IFNg SP-002

Preferred Label : Ad5-encoding IFNg SP-002;

NCIt synonyms : Adenovirus-5 Vector-encoding Human Interferon Gamma SP-002; Adenoviral Vector Ad5-hIFNg SP-002;

NCIt definition : A replication deficient adenovirus type 5 (Ad5) vector encoding for the cytokine human interferon gamma (IFNg; IFN-gamma), with potential antineoplastic and immunomodulating activities. Upon intratumoral administration, Ad5-encoding IFNg SP-002 expresses human IFNg, which binds to and activates the cell-surface IFN-gamma receptor and may stimulate an antiproliferative natural killer (NK) cell response against tumor cells and induce tumor cell apoptosis.;

Molecule name : SP 002; SP-002;

Details

Origin ID

C215074;

concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

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