Preferred Label : Phosphorylated Serine-Protein Kinase ATM;
NCIt synonyms : Phosphorylated Ataxia Telangiectasia Mutated Protein; Phosphorylated Ataxia Telangiectasia Protein; Phosphorylated ATM; p-ATM; Phospho-ATM; pATM; Phosphorylated ATM Serine/Threonine Protein Kinase;
NCIt definition : A post-translationally modified form of serine-protein kinase ATM where one or more
serine or threonine residues are phosphorylated. DNA-damage stimulates phosphorylation
and autophosphorylation of serine residues in this protein and activates its kinase
activity, which promotes DNA repair and cell cycle checkpoint signaling.;
Origin ID : C214884;
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