HLA Class II Histocompatibility Antigen, DRB1-14 Beta Chain

Preferred Label : HLA Class II Histocompatibility Antigen, DRB1-14 Beta Chain;

NCIt synonyms : HLA-DR14 Antigen; DRB1*14; DR14; Human Leukocyte Antigen DRB1*14; HLA Class II Histocompatibility Antigen, DRB1*14 Beta Chain; HLA-DRB1*14; DR-14;

NCIt related terms : HLA-DR14;

NCIt definition : HLA class II histocompatibility antigen, DRB1-14 beta chain (266 aa, 30 kDa) is encoded by the human HLA-DRB1 gene. This protein plays a role in antigen presentation to alpha-beta T-helper cells.;

Alternative definition : CDISC: The human leukocyte antigen serotype DR14 from the HLA-DR serotype group encoded by the HLA-DRB1 gene.;

NCIt note : There are at least 366 subserotypes of the HLA class II histocompatibility antigen (HLA), DRB1-14 beta chain.;

Details

Origin ID

C213688;

OMIM relation
- Major histocompatibility complex, class II, dr beta-1 [OMIM gene]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- HLA-DRB1 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
- MHC Class II Gene [NCIt concept]
gene_product_expressed_in_tissue
- CD4-Positive T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- HLA Complex [NCIt concept]
- Transmembrane Protein [NCIt concept]
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- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antigen Presentation [NCIt concept]
- Immune Response Process [NCIt concept]
- Immune System Process [NCIt concept]
- Immunoregulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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