" /> HLA Class I Histocompatibility Antigen, B-27 Alpha Chain - CISMeF





Preferred Label : HLA Class I Histocompatibility Antigen, B-27 Alpha Chain;

NCIt synonyms : HLA-B Histocompatibility Type Antigen 27; Major Histocompatibility Complex, Class I, B27 Antigen; HLA Class I Histocompatibility Antigen, B*27 Alpha Chain; MHC Class I Antigen B*27; HLA-B27; HLA-B*27; HLA-B Class I Antigen 27; Human Leukocyte Antigen B27;

NCIt related terms : HLA-B27 ANTIGEN;

NCIt definition : HLA class I histocompatibility antigen, B-27 alpha chain (362 aa, 40 kDa) is encoded by the human HLA-B gene. This protein is involved in the presentation of viral epitopes to CD8-positive T-lymphocytes. Expression of this serotype is associated with ankylosing spondylitis and other inflammatory diseases.;

Alternative definition : CDISC: The human leukocyte antigen serotype B27 from the HLA-B serotype group encoded by the HLA-B gene.;

NCIt note : There are at least 436 subserotypes of the HLA class I histocompatibility antigen (HLA), B-27 alpha chain. (IPD-IMGT/HLA Allele List and Allele Query Tool);

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28/07/2025


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