NCIt definition : Human LEUTX wild-type allele is located in the vicinity of 19q13.2 and is approximately
10 kb in length. This allele, which encodes paired-like homeodomain transcription
factor LEUTX protein, plays a role in the transition from maternal to zygotic genome
transcription during embryogenesis. Rearrangements involving this gene and the CIC
gene are associated with angiosarcoma, anaplastic ganglioglioma, anaplastic astrocytoma
with epithelioid glioblastoma multiforme (GBM) features and CIC-rearranged sarcomas.;