Preferred Label : CIC/MEGF8 Fusion Gene;
NCIt synonyms : Capicua Transcriptional Repressor/Multiple EGF Like Domains 8 Fusion Gene; CIC::MEGF8 Fusion Gene; Capicua Transcriptional Repressor-Multiple EGF Like Domains 8 Fusion Gene; CIC-MEGF8 Gene Rearrangement; CIC-MEGF8 Fusion Gene;
NCIt definition : A fusion gene that results from an as of yet unidentified chromosomal rearrangement
involving 19q13.2 that fuses the CIC gene with the MEGF8 gene. This fusion may be
associated with melanoma.;
NCIt note : CIC/MEGF8 fusion was identified in validated driver mutation-negative melanomas using
an Archer FusionPlex custom panel and confirmed by RT-PCR; the putative fusion protein
has not been observed.;
Origin ID : C213503;
concept_is_in_subset
- related_to_genetic_biomarker
