NTRK Family Gene

Preferred Label : NTRK Family Gene;

NCIt synonyms : NTRK Gene; Tropomyosin Receptor Kinase Family Gene; TRK Family Gene; Neurotrophic Tyrosine Receptor Kinase Family Gene; NTRK; Neurotrophic Tyrosine Receptor Kinase Gene; TRK Gene; Tropomyosin Receptor Kinase Gene;

NCIt definition : A family of genes that encode the tropomyosin receptor kinase (TRK) proteins, receptor tyrosine kinases that play a role in intracellular signaling and the development and function of the nervous system. Rearrangement and mutation involving these genes are associated with cancer.;

Details

Origin ID

C213194;

concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Pediatric Oncology Target Genes/Proteins Terminology [NCIt concept]
gene_encodes_gene_product
- NTRK Family Protein [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_involved_in_molecular_abnormality
- Activating NTRK Family Fusion Gene Mutation [NCIt concept]
- Activating NTRK Family Gene Mutation [NCIt concept]
- Activating NTRK Family Point Mutation [NCIt concept]
- Activating NTRK2 Gene Mutation [NCIt concept]
- Deleterious NTRK Family Gene Mutation [NCIt concept]
- NTRK Family Gene Mutation [NCIt concept]
- NTRK Gene Amplification [NCIt concept]
- NTRK Gene Rearrangement [NCIt concept]
- NTRK1 Gene Amplification [NCIt concept]
- NTRK1 Gene Mutation [NCIt concept]
- NTRK1 Gene Rearrangement [NCIt concept]
- NTRK1 Gene Translocation [NCIt concept]
- NTRK1 NM_001012331.1:c.1792C>T [NCIt concept]
- NTRK1 NM_001012331.1:c.1820G>T [NCIt concept]
- NTRK2 Gene Amplification [NCIt concept]
- NTRK2 Gene Mutation [NCIt concept]
- NTRK2 Gene Rearrangement [NCIt concept]
- NTRK3 Gene Amplification [NCIt concept]
- NTRK3 Gene Mutation [NCIt concept]
- NTRK3 Gene Rearrangement [NCIt concept]
- t(12;15)(p13;q25) [NCIt concept]
gene_plays_role_in_process
- Ligand Binding [NCIt concept]
- Neural Development [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
genetic_biomarker_related_to
- NTRK Family Fusion Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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