Conjunctival WNT-Activated Deep Penetrating/Plexiform Melanocytoma (Nevus)

Preferred Label : Conjunctival WNT-Activated Deep Penetrating/Plexiform Melanocytoma (Nevus);

NCIt definition : A benign melanocytic neoplasm that arises from the conjunctiva and is composed of spindle and/or epithelioid melanocytes and melanophages. It is caused by the combined activation of the WNT signaling and MAP-kinase pathways. It rarely progresses to melanoma.;

Neoplastic status : Benign;

Details

Origin ID

C213091;

Disease excludes abnormal cell
- Malignant Cell [NCIt concept]
Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Excludes anatomical site(s)
- Lymphatic System [NCIt concept]
Has associated anatomic sites
- Adnexa [NCIt concept]
- Conjunctiva [NCIt concept]
- Eye [NCIt concept]
- Head and Neck [NCIt concept]
- Ocular Adnexa [NCIt concept]
disease_excludes_finding
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Benign Cellular Infiltrate [NCIt concept]
- Darkly Pigmented Melanophages Present [NCIt concept]
- MAPK Pathway Activated [NCIt concept]
- WNT Pathway Activated [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_primary_anatomic_site
- Conjunctiva [NCIt concept]
- Eye [NCIt concept]
- Head and Neck [NCIt concept]
- Ocular Adnexa [NCIt concept]

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