Preferred Label : Immunogenic Cell Death Inducer CAN2109;
NCIt synonyms : ICD Inducer CAN2109;
NCIt definition : A long-acting, bi-functional immunogenic cell death (ICD) inducer, with potential
immunostimulating and antineoplastic activities. Upon intratumoral (IT) administration,
ICD inducer CAN2109 may directly kill tumor cells through as of yet undisclosed mechanism
of action (MoA). This releases tumor neoantigens, which may stimulate the host immune
system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing
the neoantigens, resulting in tumor cell lysis. CAN2109 retains in the tumor microenvironment
(TME) for a long time with minimal release to the systemic circulation after IT administration.;
Molecule name : CAN 2109; CAN-2109;
Origin ID : C212937;
concept_is_in_subset
