KMT2A/FOXO4 Fusion Gene

Preferred Label : KMT2A/FOXO4 Fusion Gene;

NCIt synonyms : KMT2A-FOXO4 Fusion Gene; MLL/AFX Fusion Gene; MLL/FOXO4 Fusion Gene; MLL-AFX Fusion Gene; KMT2A::FOXO4 Fusion Gene; MLL-FOXO4 Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(X;11)(q13;q23) that fuses the KMT2A gene downstream of the forkhead domain sequence for the FOXO4 gene. This chromosomal rearrangement is associated with both acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) in infants and young children.;

Details

Origin ID

C212138;

concept_is_in_subset
- Pediatric Oncology Target Molecular Abnormalities Terminology [NCIt concept]
related_to_genetic_biomarker
- FOXO4 Gene [NCIt concept]
- KMT2A Gene [NCIt concept]

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