Recombinant Corticotropin

Preferred Label : Recombinant Corticotropin;

NCIt synonyms : Adrenocorticotropic Hormone; Adrenocorticotropin; Therapeutic ACTH; Therapeutic Corticotropin;

NCIt related terms : CORTICOTROPIN; Acthar; ACTH;

NCIt definition : A recombinant peptide hormone chemically identical to or similar to human polypeptide hormone corticotropin (adrenocorticotropic hormone; ACTH). Secreted by the anterior pituitary gland, circulating ACTH stimulates the adrenal cortex to secrete adrenocortical steroids, especially cortisone, which elevate blood pressure in response to stress. With normally functioning adrenal glands, recombinant corticotropin could be used to achieve pharmacologic effects similar to those from cortisone administration.;

UNII : K0U68Q2TXA;

CAS number : 12427-33-7;

Drug name : Acthar;

NSC code : 16894; 25933; 25934;

ChEBI ID : CHEBI:3892;

Codes from synonyms : NSC0025934;

Détails

Origin ID

C212;

UMLS CUI

C1523997;

Automatic exact mappings (from CISMeF team)
- Corticotropin [LOINC Challenge]
- Corticotropin [ICHI extension code]
- proopiomelanocortin [ORDO Gene]
- proopiomelanocortin [HGNC gene]
Currated CISMeF NLP mapping
- ACTH [ICD-11 Extension code]
- ACTH [MedDRA LLT]
- Adrenocorticotropic hormone [MedDRA LLT]
- Adrenocorticotropic hormone (substance) [SNOMED CT concept]
- Adrenocorticotropin [FMA entity]
- Adrenocorticotropin [MedDRA LLT]
- Corticotrophin [MedDRA LLT]
- Corticotropin [ICD-11 Extension code]
- Corticotropin [FMA entity]
- Corticotropin [MedDRA LLT]
- adrenocorticotropic hormone [MeSH Descriptor]
- adrenocorticotropic hormone [MeSH concept]
- adrenocorticotropic hormone [SNOMED Notion]
- corticotropin [Substance BNPC]
- obsolete adrenocorticotropin [GO term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Validated automatic mappings to BTNT
- acth [ATC Code]
- corticotropin [ATC Code]
Validated automatic mappings to NTBT
- Corticotropin [LOINC component]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
is_component_of_chemotherapy_regimen
- Corticotropin/Cyclophosphamide [NCIt concept]

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