Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor

Preferred Label : Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor;

NCIt synonyms : SDH-Deficient GIST; Succinate Dehydrogenase-Mutated Gastrointestinal Stromal Tumor; SDH-Mutated GIST;

NCIt definition : A gastrointestinal stromal tumor characterized by the presence of mutations in the SDH genes and absence of mutations in the KIT and PDGFRA genes. It has an epithelioid morphology and a multinodular growth pattern.;

Neoplastic status : Undetermined;

Détails

Origin ID

C211873;

Disease excludes normal cell origin
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
Has associated anatomic sites
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Connective and Soft Tissue Cell [NCIt concept]
- Neoplastic Epithelioid Stromal Cell [NCIt concept]
- Neoplastic Stromal Cell [NCIt concept]
disease_has_finding
- Multinodular Pattern [NCIt concept]
disease_has_molecular_abnormality
- SDH Complex Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- Connective and Soft Tissue Cell [NCIt concept]
- Interstitial Cell of Cajal [NCIt concept]
- Stromal Cell [NCIt concept]
disease_has_primary_anatomic_site
- Connective and Soft Tissue [NCIt concept]
- Soft Tissue [NCIt concept]
disease_mapped_to_gene
- SDHA Gene [NCIt concept]
- SDHB Gene [NCIt concept]
- SDHC Gene [NCIt concept]
- SDHD Gene [NCIt concept]
disease_may_have_molecular_abnormality
- SDHA Gene Mutation [NCIt concept]
- SDHB Gene Mutation [NCIt concept]
- SDHC Gene Mutation [NCIt concept]
- SDHD Gene Mutation [NCIt concept]
may_be_associated_disease_of_disease
- Succinate Dehydrogenase-Deficient Tumor Syndrome [NCIt concept]
pathogenesis_of_disease_involves_gene
- SDHA Gene [NCIt concept]
- SDHA wt Allele [NCIt concept]
- SDHB Gene [NCIt concept]
- SDHB wt Allele [NCIt concept]
- SDHC Gene [NCIt concept]
- SDHC wt Allele [NCIt concept]
- SDHD Gene [NCIt concept]
- SDHD wt Allele [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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