Preferred Label : Gallium Ga 68-EVS459;
NCIt synonyms : Gallium Ga 68-EVS-459; [68Ga]-EVS459; [68Ga]Ga-EVS459; 68Ga-EVS459; Gallium Ga 68 EVS459;
NCIt definition : A radioconjugate composed of EVS459, a folate receptor alpha (FRa; FolRa; FOLR1)-targeting
moiety, radiolabeled with gallium Ga 68 (68Ga), with potential imaging activity upon
positron emission tomography/computed tomography (PET/CT) or PET/magnetic resonance
imaging (MRI). Upon administration of gallium Ga 68-EVS459, the FOLR1-targeting moiety
targets and binds to FOLR1 expressed on tumor cells. Upon PET/CT or PET/MRI imaging,
FOLR1-expressing tumor cells can be visualized. FOLR1 is a glycosylphosphatidylinositol
linked cell-surface glycoprotein that is widely expressed in certain cancers while
its expression is limited in normal tissues.;
Origin ID : C211690;
concept_is_in_subset
