Preferred Label : Monoclonal Antibody 703D4;
NCIt definition : A monoclonal antibody which recognizes the heterogeneous nuclear ribonucleoprotein
(hnRNP) A2/B1, a potential epithelial marker in the detection of early lung cancer,
on cell surfaces. This protein is responsible for posttranscriptional regulation of
gene expression by capping, splicing, polyadenylation, and cytoplasmic transport of
mRNAs. Its detection in bronchial lavage specimens was shown to predict predicts the
presence of a neoplasm with 96% sensitivity and 82% specificity earlier than routine
chest X rays or sputum cytology. (NCI);
Origin ID : C2106;
UMLS CUI : C1513422;
Semantic type(s)
- chemical_or_drug_has_mechanism_of_action
