Preferred Label : Prognostic Liver Secretome Signature;
NCIt synonyms : PLSec Signature; Prognostic Liver Secretome; PLSec;
NCIt definition : A non-invasive prognostic tool used predict the risk of hepatocellular carcinoma (HCC)
based on the levels of expression of 8 proteins in blood or serum samples. The protein
expression panel is comprised of six high risk markers: vascular cell adhesion protein
1 (VCAM1), insulin-like growth factor-binding protein 7 (IGFBP7), interleukin-6 receptor
subunit beta (IL6ST; gp130), matrilysin (MMP7), interleukin-6 (IL6), and C-C motif
chemokine 21 (CCL21); and two low risk markers: angiogenin (ANG) and vitamin K-dependent
protein S (PROS1).;
Origin ID : C210449;
concept_is_in_subset
related_to_genetic_biomarker