TLC ELL-12 - CISMeF

Preferred Label : TLC ELL-12;

NCIt synonyms : 1-0-Octadecyl-2-O-methyl-Sn-3-glycero-phosphocholine Liposome; ELL-12;

NCIt definition : A liposomal formulation of the ether lipid 1-O-octadecyl-2-O-methyl-sn-glycero-3-phosphocholine with potential antineoplastic activity. TLC ELL-12 induces tumor cell apoptosis via mitochondria- and caspase-mediated mechanisms. Liposomal encapsulation reduces the free agent's hemolytic toxicity. (NCI04);

Details

Origin ID

C2102;

UMLS CUI

C1313443;

Automatic exact mappings (from CISMeF team)
- TLC ELL-12 [MeSH concept]
- edelfosine [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- TLC ELL-12 [MeSH concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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