Thyroid Gland High Grade Medullary Carcinoma

Preferred Label : Thyroid Gland High Grade Medullary Carcinoma;

NCIt synonyms : Thyroid Gland High-Grade Medullary Carcinoma;

NCIt definition : A thyroid gland medullary carcinoma with at least one of the following characteristics: necrosis, 5 or more mitoses per 2 mm2, and/or a Ki-67 index equal to or greater than 5%.;

Neoplastic status : Malignant;

Details

Origin ID

C210129;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Disease may have findings
- Cold Nodule [NCIt concept]
- Metastatic Malignant Neoplasm in the Lymph Nodes [NCIt concept]
- Necrotic Change [NCIt concept]
- Organoid Pattern [NCIt concept]
- Trabecular Pattern [NCIt concept]
Excludes anatomical site(s)
- Lung [NCIt concept]
- Pituitary Gland [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Calcitonin Positive Neoplastic Cells Present [NCIt concept]
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
- Serum Calcitonin Level Increased [NCIt concept]
- Well-Circumscribed Lesion [NCIt concept]
disease_has_grade
- High Grade [NCIt concept]
disease_has_molecular_abnormality
- Activating RET Gene Mutation [NCIt concept]
disease_has_normal_cell_origin
- C-Cell [NCIt concept]
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Thyroid Gland Epithelial Tissue [NCIt concept]
- Thyroid Gland Follicle [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Neck [NCIt concept]
- Thyroid Gland [NCIt concept]
disease_mapped_to_gene
- RET Gene [NCIt concept]
disease_may_have_abnormal_cell
- Malignant Neuroendocrine Polygonal Cell [NCIt concept]
- Malignant Neuroendocrine Small Round Cell [NCIt concept]
- Malignant Neuroendocrine Spindle Cell [NCIt concept]
disease_may_have_associated_disease
- Paraneoplastic Syndrome [NCIt concept]

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