Preferred Label : Immunoadjuvant;
NCIt synonyms : Adjuvants, Immunologic; Immunologic Adjuvant; Immunologic Adjuvants;
NCIt related terms : immune adjuvant; immunological adjuvant;
NCIt definition : Adjuvants are mostly pharmacological agents of drug or biological origin used to modify
the antigenicity of immunization components, i.e., to stimulate, potentiate, or depress
the immune response or to inhibit or enhance specific subclasses of immunocytes. Adjuvants
augment, stimulate, activate, potentiate, or modulate the immune response at either
the cellular or humoral level. Classical agents (Freund's adjuvant, BCG, Corynebacterium
parvum) contain bacterial antigens. Some adjuvants are endogenous (e.g., histamine,
interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either
non-specific, resulting in increased immune responsiveness to a variety of antigens,
or antigen-specific, affecting a restricted type of immune response to a narrow group
of antigens. Since adjuvants enhance the body's immune response, they can be considered
a type of immune modulator.;
Alternative definition : NCI-GLOSS: A drug that stimulates the immune system to respond to disease.;
ChEBI ID : CHEBI:50847;
Codes from synonyms : CDR0000044883; CDR0000043987;
Origin ID : C210;
UMLS CUI : C0001551;
Currated CISMeF NLP mapping
- False automatic mappings
- Semantic type(s)
- UMLS correspondences (same concept)
