NCIt definition : A fixed combination of two protease inhibitors, lopinavir and ritonavir, used to treat
human immunodeficiency virus (HIV) infection. The ritonavir in the combination drug
increases the concentration and biological half-life of lopinavir but is not present
in sufficient concentration to act as a protease inhibitor.;
Alternative definition : NCI-GLOSS: A combination of the drugs ritonavir and lopinavir. It is used to treat
infection with HIV (the virus that causes AIDS). It is also being studied in the treatment
of some types of cancer. Lopinavir/ritonavir blocks the ability of HIV to make copies
of itself and may help other anticancer drugs work better or may block the growth
of cancer cells. Ritonavir blocks the breakdown of lopinavir. Lopinavir/ritonavir
is a type of anti-HIV agent and a type of protease inhibitor.;
Drug name : Kaletra;
Codes from synonyms : CDR0000642979; CDR0000642978;
Currated CISMeF NLP mapping