Preferred Label : Ornithine Decarboxylase Inhibitor;
NCIt synonyms : Ornithine Decarboxylase Inhibitors;
NCIt definition : Any substance that inhibits ornithine decarboxylase, an enzyme that catalyzes the
decarboxylation of ornithine, the rate-limiting, commiting reaction in polyamine synthesis.
Polyamines are important for stabilizing DNA structure, for the DNA double strand-break
repair pathway, and as antioxidants, and inhibition of ornithine decarboxylase inhibits
cell growth.;
Origin ID : C2088;
UMLS CUI : C1518618;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
