N,N-Dibenzyl Daunomycin

Preferred Label : N,N-Dibenzyl Daunomycin;

NCIt synonyms : N,N-dibenzyldaunomycin; N,N-dibenzyldaunorubicin; N,N-dibenzyl daunorubicin; N N-Dibenzyl Daunomycin;

NCIt definition : The N-alkylated analogue of the anthracycline antineoplastic antibiotic daunomycin. N,N-Dibenzyl Daunomycin interacts with topoisomerase II, thereby inhibiting DNA replication and repair and promoting DNA fragmentation. This agent is less cardiotoxic than daunomycin. (NCI04);

Details

Origin ID

C2084;

UMLS CUI

C0067345;

Currated CISMeF NLP mapping
- N,N-dibenzyldaunorubicin [MeSH concept]
- N,N-dibenzyldaunorubicin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- N,N-dibenzyldaunorubicin [MeSH concept]
- N,N-dibenzyldaunorubicin [MeSH Supplementary Concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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