BCPR Gene - CISMeF

Preferred Label : BCPR Gene;

NCIt synonyms : Breast Cancer-Related Regulator of TP53 Gene; BCPR;

CISMeF acronym : BCPR;

NCIt definition : Human BCPR wild-type allele is located in the vicinity of 17p13.3 and the length of the gene is currently unknown. This allele, which encodes breast cancer-related regulator of TP53 protein, plays a role in tumor suppression.;

NCIt note : Defined by D17S926, D17S695, and D17S849, which map close together in a region of high loss of heterozygosity (60%), BCPR gene appears to be associated with over expression of p53 mRNA, suggesting a gene located some twenty megabases telomeric to TP53 that regulates its expression. Lesions of this regulatory gene seem to be involved in most breast cancers.; Interim Gene Symbol and Name;

Details

Origin ID

C20776;

UMLS CUI

C1332403;

C1704961;

Automatic exact mappings (from CISMeF team)
- Breast cancer-related regulator of tp53 [OMIM Phenotype]
OMIM relation
- Breast cancer-related regulator of tp53 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- Breast cancer-related regulator of tp53 [OMIM Phenotype]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17p13.3 [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Tumor Suppression [NCIt concept]
- Tumorigenesis [NCIt concept]

Keyword's position in hierarchy(ies) :

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