Preferred Label : FABP Family Gene;
NCIt definition : These genes encode the intracellular fatty acid-binding proteins (FABPs). Fatty acid
metabolism in mammalian cells depends on a flux of fatty acids, between the plasma
membrane and mitochondria or peroxisomes for beta-oxidation, and between other cellular
organelles for lipid synthesis. FABPs are divided into at least three distinct types,
namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and
at least 3 different FABPs play a role as transport vehicles of these hydrophobic
compounds throughout the cytoplasm. They may participate in the uptake, intracellular
metabolism and/or transport of long-chain fatty acids. They may also be responsible
in the modulation of cell growth and proliferation. (from LocusLink 2170);
Origin ID : C20735;
UMLS CUI : C1333529;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
