X-Chromosome Inactivation

Preferred Label : X-Chromosome Inactivation;

NCIt synonyms : X Inactivation; X Chromosome Inactivation; X-Inactivation; Lyonization;

NCIt definition : A human early embryonic event in which in any given cell one of a female's two X chromosomes becomes inactivated and converted into a Barr body. After inactivation has occurred, all descendants of that cell have the same inactivated X chromosome. Thus, X-inactivation creates cell clones with differing effective gene content. An organism whose cells vary in effective gene content and hence in the expression of a trait, is called a genetic mosaic.;

Details

Origin ID

C20674;

UMLS CUI

C0043297;

Automatic exact mappings (from CISMeF team)
- dosage compensation by inactivation of X chromosome [GO term]
Currated CISMeF NLP mapping
- X chromosome inactivation [LOINC component]
- X chromosome inactivation [MeSH concept]
- x chromosome inactivation [MeSH Descriptor]
Semantic type(s)
- Genetic Function [UMLS semantic type]
UMLS correspondences (same concept)
- X chromosome inactivation [MeSH concept]
- dosage compensation by inactivation of X chromosome [GO term]
- x chromosome inactivation [MeSH Descriptor]
biological_process_has_associated_location
- Human Chromosome X [NCIt concept]
biological_process_involves_gene_product
- YTH Domain-Containing Protein 1 [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
process_involves_gene
- YTHDC1 Gene [NCIt concept]
- YTHDC1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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