Preferred Label : Transcription Coactivator Gene;
NCIt definition : RNA polymerase II transcription of Class II genes involves the TFIID transcription
complex comprised of general factors, including TBP, TFIIA, TFIIB, TFIID, TFIIE, TFIIF,
TFIIG/J, and TFIIH, as well as gene-specific factors that include TAFs, which interact
with regulatory protein activation domains to enhance transcription. A second group
of cofactors includes PC1, PC2, and PC3, which have a strong positive influence on
transcription. The combined action of general and gene-specific regulators encoded
by Transcription Coactivator Genes enhances gene expression. (NCI);
Origin ID : C20673;
UMLS CUI : C1336777;
Semantic type(s)
- gene_encodes_gene_product
- gene_found_in_organism
- gene_plays_role_in_process
