NCIt definition : A subgrouping of the inflammatory myopathies characterized by severe proximal weakness,
elevated creatine kinase levels, and myofiber necrosis. They can be further distinguished
by the presence or absence of associated autoantibodies, including anti-3-hydroxy-3-methylglutaryl-CoA
reductase (HMGCR), anti-signal recognition particle (SRP), and antibody negative immune-mediated
necrotizing myopathy (IMNM).;