Preferred Label : TFIIF Subunit Gene;
NCIt definition : Human TFIIF Subunit Genes, GTF2F1 Gene and GTF2F2 Gene, encode similar alpha (517-aa,
58-kDa, phosphorylated) and beta (249-aa, 28-kDa) subunits of heterodimeric nuclear
general transcription initiation factor TFIIF, which binds to and recruits RNA polymerase
II to the initiation complex in collaboration with TFIIB. The beta subunit shows ATP-dependent
DNA-helicase activity and the region that binds RNA polymerase exhibits similarities
with prokaryotic sigma factors. (NCI);
Origin ID : C20651;
UMLS CUI : C1336614;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
