Preferred Label : PEAK1 wt Allele;
NCIt synonyms : Pseudopodium Enriched Atypical Kinase 1 wt Allele; SGK269; KIAA2002; NKF3 Kinase Family Member Gene;
NCIt definition : Human PEAK1 wild-type allele is located in the vicinity of 15q24.3 and is approximately
320 kb in length. This allele, which encodes inactive tyrosine-protein kinase PEAK1
protein, plays a role in the mediation of EGFR signaling and the modulation of focal
adhesion elongation. A frameshift mutation may be associated with childhood B-cell
acute lymphoblastic leukemia.;
NCI Metathesaurus CUI : CL1928537;
GenBank Accession Number : NM_001385026;
PubMed : 21680795;
Origin ID : C206185;
OMIM relation
- gene_found_in_organism
- gene_plays_role_in_process
