Preferred Label : ATTR Amyloidosis;
NCIt synonyms : Transthyretin Amyloidosis;
NCIt definition : A disorder caused by changes in the structure of transthyretin protein, affecting
its ability to form tetramers. The tetramers break down and form strands of amyloid
fibrils. The fibrils clump together and form amyloid deposits in tissues, causing
irreversible damage. It can be hereditary, caused by mutations in the TTR gene or
age-related.;
Origin ID : C205628;
concept_is_in_subset
- disease_has_finding
