Preferred Label : TFIID Subunit Gene;
NCIt definition : Human transcription initiation factor TFIID is composed of the TATA-binding protein
(TBP) and at least 13 TBP-associated factors (TAFs) that collectively or individually
are involved in activator-dependent transcription. Initiation of transcription by
RNA polymerase II requires the ordered assembly of basal transcription factors including
TFIIA, TFIIB, TATA-binding protein (TBP), TFIIE, TFIIF, TFIIG/TFIIJ, and TFIIH/BTF2
into the TFIID complex. Different activators may interact with specific TAFs to allow
the assembly of functionally distinct TFIID complexes that can control transcription
of different genes. (NCI);
Origin ID : C20543;
UMLS CUI : C1336612;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
