RCBTB1 wt Allele

Preferred Label : RCBTB1 wt Allele;

NCIt synonyms : CLLL7; E4.5; CLLD7; FLJ10716; Chronic Lymphocytic Leukemia Deletion Region Gene 7; GDP/GTP Exchange Factor-Like Protein Gene; Regulator of Chromosome Condensation (RCC1) and BTB (POZ) Domain Containing Protein 1 Gene; CLL Deletion Region Gene 7; RCC1 and BTB Domain Containing Protein 1 wt Allele; RDEOA; GDP/GTP Exchange Factor (GEF)-Like Protein Gene; GLP;

NCIt definition : Human RCBTB1 wild-type allele is located in the vicinity of 13q14.2 and is approximately 54 kb in length. This allele, which encodes RCC1 and BTB domain-containing protein 1, may be involved in the transcriptional regulation of cell cycle genes through chromatin remodeling. Mutations in the gene are associated with retinal dystrophy with or without extraocular anomalies. This gene is located in a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies.;

NCI Metathesaurus CUI : CL1927387;

GenBank Accession Number : AF334406;

Details

Origin ID

C204945;

OMIM relation
- Rcc1 domain- and btb domain-containing protein 1 [OMIM gene]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 13q14.2 [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Chromatin Structural Process [NCIt concept]
- Gene Regulation Process [NCIt concept]

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