" /> Indibulin - CISMeF





Preferred Label : Indibulin;

NCIt synonyms : D 24851; N-(Pyridin-4-yl)-(1-(4-chlorobenzyl)indol-3-yl)glycoxylamide;

NCIt definition : A synthetic small molecule with antimitotic and potential antineoplastic activities. Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis. This agent has been shown to be active against multidrug-resistant (MDR) and taxane- resistant tumor cell lines.;

UNII : 80K4H2RB8P;

InChIKey : SOLIIYNRSAWTSQ-UHFFFAOYSA-N;

CAS number : 204205-90-3;

Molecule name : D-24851; D 24851; ZIO-301;

Chemical formula : C22H16ClN3O2;

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28/07/2025


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