Low-CSD Melanoma, Superficial Spreading Melanoma Subtype

Preferred Label : Low-CSD Melanoma, Superficial Spreading Melanoma Subtype;

NCIt synonyms : Low-CSD Melanoma/Superficial Spreading Melanoma; SSM; Pagetoid Melanoma; Low-CSD Melanoma, Superficial Spreading Melanoma (SSM); Low-CSD Melanoma, SSM Subtype; Cutaneous Superficial Spreading Melanoma; Superficial Spreading Melanoma of the Skin; Low-CSD Melanoma, Superficial Spreading Melanoma; Low-CSD Melanoma/SSM;

NCIt related terms : Superficial Spreading Cutaneous (Skin) Melanoma; Superficial spreading melanoma;

NCIt definition : A cutaneous melanoma that develops on sun exposed sites with low cumulative sun damage (CSD). It is characterized by a prominent junctional and intraepidermal component with intraepidermal proliferation of individual atypical melanocytes and formation of nests of atypical melanocytes along the dermal-epidermal junction. The dermal component is composed of atypical melanocytes that fail to mature. The atypical melanocytes have large nuclei, prominent nucleoli, and eosinophilic or lightly pigmented cytoplasm. It is the most common melanoma subtype in the Western world.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1927043;

Details

Origin ID

C204843;

UMLS CUI

C0334438;

Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
- Vertical Growth Phase [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Superficial spreading malignant melanoma of skin (disorder) [SNOMED CT concept]
- Superficial spreading melanoma [MedDRA LLT]
- Superficial spreading melanoma [HPO term]
- Superficial spreading melanoma [ICD-O code]
- Superficial spreading melanoma (morphologic abnormality) [SNOMED CT concept]
- Superficial spreading melanoma stage unspecified [MedDRA Preferred Term]
- superficial spreading malignant melanoma [Disease (Nov.)]
- superficial spreading melanoma [SNOMED Notion]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.1 Morphology Terminology [NCIt concept]
- Mapped ICDO3.1 Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology PT Terminology [NCIt concept]
- Mapped ICDO3.2 Morphology Terminology [NCIt concept]
- Mapped ICDO3.2 Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Skin with High Degree of Cumulative Sun Damage [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Melanoma Cell [NCIt concept]
- Melanoma Cell with Large Nucleus and Abundant Pale Cytoplasm [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Cutaneous Involvement [NCIt concept]
- Intermittent Sun Exposure [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Pagetoid Proliferation [NCIt concept]
- Radial Growth Phase [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Skin Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]
disease_mapped_to_gene
- BRAF Gene [NCIt concept]
disease_may_have_molecular_abnormality
- BRAF Gene Mutation [NCIt concept]

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