Preferred Label : Systematic Evolution of Ligands by Exponential Enrichment;
NCIt synonyms : SELEX;
NCIt definition : A method for isolating single-stranded DNAs or RNAs (aptamers) with high-affinity
to a target protein from a large library with random sequences. The target protein
is expressed as a fusion with streptavidin-binding peptide and is the mixed with a
pooled library of DNA or RNA ligands containing a 14bp randomized region (14N), and
a 5 bp barcode that uniquely identifies the individual SELEX sample. Partially nested
primers are used in successive SELEX rounds.;
Origin ID : C204826;
UMLS CUI : C1567938;
Semantic type(s)
- UMLS correspondences (same concept)
