Spitz Tumor - CISMeF

Preferred Label : Spitz Tumor;

NCIt synonyms : Spitz Neoplasm;

NCIt definition : A term that refers to a group of melanocytic neoplasms that are composed of epithelioid and/or spindle cells and extend from the epidermis into the reticular dermis, often in a wedge-shaped configuration. They are usually associated with oncogenic mutations that activate the MAP-kinase pathway. This category includes Spitz nevus, Spitz melanocytoma, and Spitz melanoma.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL1926994;

Details

Origin ID

C204790;

UMLS CUI

C5909991;

Disease may have findings
- HMB-45-Positive Neoplastic Cells Present [NCIt concept]
- MAPK Pathway Activated [NCIt concept]
- S-100-Positive Neoplastic Cells Present [NCIt concept]
Has associated anatomic sites
- Integumentary System [NCIt concept]
- Skin [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_has_abnormal_cell
- Neoplastic Cell [NCIt concept]
- Neoplastic Melanocyte [NCIt concept]
disease_has_finding
- Cutaneous Involvement [NCIt concept]
disease_has_normal_cell_origin
- Melanocyte [NCIt concept]
disease_has_normal_tissue_origin
- Skin Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Skin [NCIt concept]

Keyword's position in hierarchy(ies) :

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