Preferred Label : Crisaborole Ointment;
NCIt definition : A topical ointment formulation composed of crisaborole, a boron-containing phosphodiesterase
4 (PDE4) inhibitor, with potential immunomodulating activity. Upon topical administration
of the crisaborole ointment to the affected area(s), crisaborole targets, binds to
and inhibits PDE4, which increases intracellular cyclic adenosine monophosphate (cAMP)
levels. This decreases inflammation in the skin. PDE4 inhibition may reduce cetuximab-related
skin toxicity and atopic dermatitis.;
Drug name : Eucrisa;
NCI Metathesaurus CUI : CL1926426;
Origin ID : C204175;
UMLS CUI : C4301784;
Semantic type(s)
- concept_is_in_subset
- has_target
