Actinomycin Antineoplastic Antibiotic

Preferred Label : Actinomycin Antineoplastic Antibiotic;

NCIt synonyms : Actinomycins; Actinomycin Antibiotic;

NCIt definition : A chromopeptide antineoplastic antibiotic isolated from the bacterial genus Streptomyces. Actinomycin antibiotics inhibit DNA replication and RNA and protein synthesis by various mechanisms such as intercalating into the minor groove of DNA and interfering with the function of topoisomerase II.;

Details

Origin ID

C204;

UMLS CUI

C0001259;

Automatic exact mappings (from CISMeF team)
- Dactinomycin (substance) [SNOMED CT concept]
- Product containing dactinomycin (medicinal product) [SNOMED CT concept]
- Suborder Actinomycineae (organism) [SNOMED CT concept]
- actinomycines [ATC Code]
- dactinomycin [SNOMED Notion]
- dactinomycin [MeSH Descriptor]
Currated CISMeF NLP mapping
- actinomycin [Substance BNPC]
- actinomycin [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Antibiotic [UMLS semantic type]
UMLS correspondences (same concept)
- actinomycin [Substance BNPC]
- actinomycin [MeSH concept]
- actinomycines [ATC Code]

Keyword's position in hierarchy(ies) :

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