Preferred Label : Protein Phosphatase 2A Subunit Gene;
NCIt synonyms : Protein Phosphatase-2A Subunit Gene;
NCIt definition : The Protein Phosphatase 2A Subunit Genes encodes 3 subunits (A, B, and C) of Protein
Phosphatase 2A (PP2A) holoenzyme, a heterotrimeric serine/threonine phosphatase. The
structural A subunit and the catalytic C subunit form a catalytic core, while substrate
specificity is directed by the B subunit. PP2A exerts regulatory control over the
initiation of DNA replication and has a particularly complex set of regulatory subunits
controlling its function and localization.;
Origin ID : C20396;
UMLS CUI : C1335538;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
