Preferred Label : Additive Effect;
NCIt definition : Two or more drugs working together to produce a combined effect that is equal to the
effects.;
Alternative definition : MRCT-Ctr: The combined effect when two or more things are used together. (https://mrctcenter.org/glossaryterm/additive-effect/); CDISC-GLOSS: An interaction between bioactive compounds or drugs that is deemed to
be equal to the sum of the individual components. NOTE: The terms additivity, synergism,
and antagonism should be used with care, unless the specific pharmacological pathways
or mechanisms of action of the investigated drugs are known. [After Calzetta L, Koziol-White
C. Pharmacological interactions: Synergism, or not synergism, that is the question.
Curr Res Pharmacol Drug Discov. 2021 Aug 11;2:100046.] See also synergistic effect,
antagonistic effect, drug interaction.;
NCI Metathesaurus CUI : CL1926544;
Origin ID : C203914;
UMLS CUI : C5909495;
Semantic type(s)
concept_is_in_subset