" /> Additive Effect - CISMeF





Preferred Label : Additive Effect;

NCIt definition : Two or more drugs working together to produce a combined effect that is equal to the effects.;

Alternative definition : MRCT-Ctr: The combined effect when two or more things are used together. (https://mrctcenter.org/glossaryterm/additive-effect/); CDISC-GLOSS: An interaction between bioactive compounds or drugs that is deemed to be equal to the sum of the individual components. NOTE: The terms additivity, synergism, and antagonism should be used with care, unless the specific pharmacological pathways or mechanisms of action of the investigated drugs are known. [After Calzetta L, Koziol-White C. Pharmacological interactions: Synergism, or not synergism, that is the question. Curr Res Pharmacol Drug Discov. 2021 Aug 11;2:100046.] See also synergistic effect, antagonistic effect, drug interaction.;

NCI Metathesaurus CUI : CL1926544;

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09/05/2025


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