T-cell Engaging Antibody

Preferred Label : T-cell Engaging Antibody;

NCIt synonyms : T-cell-engaging Antibody; TCE; T Cell Engager;

NCIt definition : Any antibody that simultaneously binds to the CD3 subunit within the T-cell receptor (TCR) complex expressed on T-cells and at least one tumor-associated antigen (TAA) expressed on tumor cells.;

NCI Metathesaurus CUI : CL1926474;

Details

Origin ID

C203828;

UMLS CUI

C5891064;

Automatic exact mappings (from CISMeF team)
- craniocerebral trauma [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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