MOCS1 wt Allele

Preferred Label : MOCS1 wt Allele;

NCIt synonyms : Molybdenum Cofactor Synthesis 1 wt Allele; MOCOD; Cell Migration-Inducing Gene 11; MOCS1A; MOCS1B; Molybdenum Cofactor Synthesis Gene 1; MIG11;

NCIt definition : Human MOCS1 wild-type allele is located in the vicinity of 6p21.2 and is approximately 35 kb in length. This allele, which encodes molybdenum cofactor biosynthesis protein 1, is involved in the biosynthesis of cyclic pyranopterin monophosphate (cPMP). Mutation of the gene is associated with molybdenum cofactor deficiency A.;

NCIt note : The MOCS1 gene locus was initially thought to produce transcripts for MOCS1A and MOCS1B from non-overlapping reading frames within a bicistronic transcript. However, the only isoform MOCS1A is produced from this bicistronic transcript. A monocistronic mRNA can produce several isoforms of both MOCS1A and MOCS1B due to alternative splicing. (EntrezGene and OMIM);

NCI Metathesaurus CUI : CL1926483;

GenBank Accession Number : AJ224328;

Details

Origin ID

C203810;

UMLS CUI

C5891019;

OMIM relation
- Molybdenum cofactor synthesis gene 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 6p21.2 [NCIt concept]
gene_is_element_in_pathway
- Folate Biosynthesis Pathway [NCIt concept]
gene_plays_role_in_process
- Biosynthetic Process [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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