Preferred Label : Nanoparticle Encapsulated AChR Epitopes CNP-106;
NCIt synonyms : CNPs Encapsulating AChR Peptides CNP-106;
NCIt definition : A nanoparticle-based formulation consisting of an antigenic acetylcholine receptor
(AChR) peptide pool dispersed within a negatively charged polymer matrix of poly(dl-lactide-co-glycolide)
(PLGA) particles, with potential immunomodulatory activity. Upon administration, nanoparticle
encapsulated AChR epitopes CNP-106 binds to inflammatory cells and delivers multiple
AChR epitopes, which initiates tolerogenic immune reprogramming. This may induce and
promote antigen-specific tolerance against AChR, which may prevent neuromuscular junction
damage and dysfunction that results from autoimmunity targeting AChR.;
Molecule name : CNP 106; CNP-106;
NCI Metathesaurus CUI : CL1922482;
Origin ID : C203653;
UMLS CUI : C5908013;
Semantic type(s)
- concept_is_in_subset
