Paranasal Sinus Small Cell Neuroendocrine Carcinoma

Preferred Label : Paranasal Sinus Small Cell Neuroendocrine Carcinoma;

NCIt definition : A rare neuroendocrine carcinoma that arises from the paranasal sinuses and is composed of malignant small cells. The mitotic count is more than 10 per 2 mm2 and/or the Ki-67 index is more than 20%.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1922169;

Details

Origin ID

C203004;

UMLS CUI

C5908903;

Disease excludes abnormal cell
- Large Osteoclastic Giant Cell [NCIt concept]
- Malignant Neuroendocrine Large Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Endothelial Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
Disease excludes normal cell origin
- Endothelial Cell [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- Epistaxis [NCIt concept]
- Neuron-Specific Enolase Positive Neoplastic Cells Present [NCIt concept]
- Pain [NCIt concept]
- Rhinorrhea [NCIt concept]
Excludes anatomical site(s)
- Lung [NCIt concept]
Has associated anatomic sites
- Head and Neck [NCIt concept]
- Paranasal Sinus [NCIt concept]
- Sinonasal Tract [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Well Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_abnormal_cell
- Malignant Cell [NCIt concept]
- Malignant Endocrine Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Malignant Neuroendocrine Cell [NCIt concept]
- Malignant Neuroendocrine Small Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Endocrine Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Neuroendocrine Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Endocrine Differentiation [NCIt concept]
- Epithelial Component Present [NCIt concept]
- Expression of Neuroendocrine Markers Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Necrotic Change [NCIt concept]
- Neuroendocrine Differentiation [NCIt concept]
- Poorly Differentiated Neuroendocrine Lesion [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Paranasal Sinus Epithelium [NCIt concept]
disease_has_primary_anatomic_site
- Head and Neck [NCIt concept]
- Paranasal Sinus [NCIt concept]
- Sinonasal Tract [NCIt concept]
disease_may_have_molecular_abnormality
- TP53 Gene Inactivation [NCIt concept]

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